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Home - Products - Endocrinology/Hormones - 5-HT Receptor - NAN-190 hydrobromide

NAN-190 hydrobromide

CAS No. 115338-32-4

NAN-190 hydrobromide ( NAN190 hydrobromide;NAN 190 hydrobromide )

Catalog No. M10539 CAS No. 115338-32-4

NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NAN-190 hydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.
  • Description
    NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor; antagonizes the stimulation by norepinephrine of phosphoinositide turnover in rat cortical slices.Anxiety Preclinical
  • Synonyms
    NAN190 hydrobromide;NAN 190 hydrobromide
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Anxiety

Chemical Information

  • CAS Number
    115338-32-4
  • Formula Weight
    474.39
  • Molecular Formula
    C23H28BrN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 36.23 mg/mL
  • SMILES
    COC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4C3=O.Br
  • Chemical Name
    1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-, hydrobromide (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Claustre Y, et al. Eur J Pharmacol. 1991 Oct 29;204(1):71-7.
2. Zhang J, et al. J Neurosci. 2010 Feb 17;30(7):2433-41.
3. Glennon RA, et al. J Med Chem. 1988 Oct;31(10):1968-71.
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