NAN-190 hydrobromide
CAS No. 115338-32-4
NAN-190 hydrobromide ( NAN190 hydrobromide;NAN 190 hydrobromide )
Catalog No. M10539 CAS No. 115338-32-4
NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 29 | Get Quote |
|
10MG | 41 | Get Quote |
|
50MG | 67 | Get Quote |
|
100MG | 86 | Get Quote |
|
200MG | 156 | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNAN-190 hydrobromide
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NoteResearch use only, not for human use.
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Brief DescriptionNAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.
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DescriptionNAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor; antagonizes the stimulation by norepinephrine of phosphoinositide turnover in rat cortical slices.Anxiety Preclinical
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SynonymsNAN190 hydrobromide;NAN 190 hydrobromide
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number115338-32-4
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Formula Weight474.39
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Molecular FormulaC23H28BrN3O3
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Purity>98% (HPLC)
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SolubilityDMSO: 36.23 mg/mL
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SMILESCOC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4C3=O.Br
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Chemical Name1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-, hydrobromide (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Claustre Y, et al. Eur J Pharmacol. 1991 Oct 29;204(1):71-7.
2. Zhang J, et al. J Neurosci. 2010 Feb 17;30(7):2433-41.
3. Glennon RA, et al. J Med Chem. 1988 Oct;31(10):1968-71.
2. Zhang J, et al. J Neurosci. 2010 Feb 17;30(7):2433-41.
3. Glennon RA, et al. J Med Chem. 1988 Oct;31(10):1968-71.
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